{"id":13950,"date":"2023-09-13T14:31:30","date_gmt":"2023-09-13T07:31:30","guid":{"rendered":"http:\/\/cosmina.co.th\/?p=13950"},"modified":"2025-10-09T13:44:15","modified_gmt":"2025-10-09T06:44:15","slug":"sh-oligopeptide-1-egf-2","status":"publish","type":"post","link":"https:\/\/cosmina.co.th\/en\/sh-oligopeptide-1-egf-2\/","title":{"rendered":"Sh-Oligopeptide-1 (EGF)"},"content":{"rendered":"<div class=\"row\"  id=\"row-1019848428\">\n\n\t<div id=\"col-1502803719\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\t<div class=\"img has-hover x md-x lg-x y md-y lg-y\" id=\"image_1618256651\">\n\t\t\t\t\t\t\t\t<div class=\"img-inner dark\" >\n\t\t\t<img decoding=\"async\" width=\"1020\" height=\"768\" src=\"https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-1062x800.png\" class=\"attachment-large size-large\" alt=\"[:th]Sh-Oligopeptide-1 (EGF)[:]\" srcset=\"https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-1062x800.png 1062w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-900x678.png 900w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-531x400.png 531w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-280x211.png 280w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-768x578.png 768w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-1536x1157.png 1536w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01-600x452.png 600w, https:\/\/cosmina.co.th\/en\/wp-content\/uploads\/Sh-Oligopeptide-1-EGF-01.png 1539w\" sizes=\"(max-width: 1020px) 100vw, 1020px\" \/>\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n<style>\n#image_1618256651 {\n  width: 100%;\n}\n<\/style>\n\t<\/div>\n\t\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1174655703\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<p><span style=\"font-family: db-heavent-mid; color: #003366;\">Sh-Oligopeptide-1 (EGF)<\/span><br \/>\n<span style=\"font-family: db-heavent-mid;\">Epidermal growth factor (EGF) plays an important role in the regulation of cell growth, proliferation and differentiation.\u00a0 Human EGF is a 6045 Da protein with 53 amino acid residues and three intramolecular disulfide bonds.\u00a0 EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor.\u00a0 The tyrosine kinase activity in turn initiates a signal transduction cascade which results in a variety of biochemical changes within the cell &#8211; a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR &#8211; that ultimately lead to DNA synthesis and cell proliferation.<\/span><\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":9488,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[296,278],"tags":[],"class_list":["post-13950","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anti-aging-anti-wrinkle-ingredients","category-ingredients"],"_links":{"self":[{"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/posts\/13950","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/comments?post=13950"}],"version-history":[{"count":0,"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/posts\/13950\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/media\/9488"}],"wp:attachment":[{"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/media?parent=13950"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/categories?post=13950"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cosmina.co.th\/en\/wp-json\/wp\/v2\/tags?post=13950"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}